What Causes a ‘Hair-on-End’ Skull?

Bone marrow hyperplasia
Explore the striking 'hair-on-end' appearance on a skull radiograph. Understand the key differential diagnoses and the underlying pathophysiological process.
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Diagnosing a Suspicious Skin Macule

Lentigo maligna
An 81-year-old woman presents with a poorly circumscribed macule with variegated pigmentation. Explore the key diagnosis that must be excluded in such cases.
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The Medusa’s Head Sign

Portal hypertension
A patient presents with prominent veins on their abdomen. What does this sign, known as caput medusae, indicate? Discover the diagnosis and treatment.
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The Blue-Grey Man

Amiodarone
A 61-year-old man presents with a strange blue-grey skin discoloration while being treated for an arrhythmia. Discover the cause of this unusual side effect.
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When a Rash Affects Vision

Herpes zoster ophthalmicus
A case of a painful facial rash leading to a left VI nerve palsy. Explore the diagnosis and management of this serious viral reactivation in the V1 dermatome.
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A Case of Traumatic Ptosis & Mydriasis

Skull fracture
A patient presents with ptosis and mydriasis after a traumatic head injury. Explore the differential diagnosis and key findings for a cranial nerve III palsy.
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What’s Blocking the Flow?

Right ureterovesical calculus
Analyze an intravenous urogram showing right-sided caliectasis, a dilated ureter, and a filling defect. What causes these classic urological findings?
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A Swollen Face and a Hoarse Voice

Superior vena cava syndrome
Explore the case of a 75-year-old man with cough, hoarseness, and facial swelling. Discover the critical diagnosis behind these alarming symptoms.
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Puzzling Pruritic Papules

Scabies
A 46-year-old woman presents with intensely itchy papular lesions in her axillae, groin, and buttocks. Explore the differential diagnosis for this pruritic rash.
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The Case of the Wandering Worm

Loa loa
A patient presents with a visible worm in their eye. Explore the diagnosis of this filarial parasite, endemic to west and central Africa. Learn the key signs.
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