A Puzzling Post-Infectious Rash

A 40-year-old man develops a scaly foot rash, Joint Pain, and red eyes after an infection. Explore the diagnosis of this classic triad of symptoms.

Keratoderma blenorrhagicum


A 40-year-old man presented with a 2-week history of scaly foot rash, joint swelling, penile rash, knee swelling, tongue changes, red eyes, and low back pain. He had had diarrhea and urethral discharge 7 days before the onset of symptoms. On examination, yellow pustules with hyperkeratosis were seen on his plantar feet. What is the name of this physical examination sign?

What is the most likely diagnosis?

Keratoderma blenorrhagicum
Palmoplantar keratoderma
Pitted keratolysis
Porokeratosis
Pustular psoriasis

HLA-B27, Keratoderma blenorrhagicum, Reactive arthritis, Spondyloarthropathy, Sterile pyuria

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