A Child’s Mysterious Cheek Lesion

A 9-year-old girl presents with a crusted plaque on her cheek, fever, and swollen lymph nodes. Explore the Differential Diagnosis and key diagnostic clues.

Primary cutaneous HSV-1 infection


A 9-year-old girl presented to the dermatology department with a 7-day history of a lesion on the left cheek and a 4-day history of fever. On physical examination, a round plaque 3 cm in diameter on an erythematous base was observed on the patient’s left cheek, with overlying crusting and a single intact vesicle. Satellite vesicles and ipsilateral cervical lymphadenopathy were also present. There were no mucosal lesions. What is the most likely diagnosis?

What is the most likely diagnosis?

Cutaneous non-tuberculous mycobacterial infection
Impetigo
Primary cutaneous HSV-1 infection
Syphilitic chancre
Tinea corporis

Dermatology, Herpes Simplex Virus, Impetigo, Pediatrics, Primary cutaneous HSV-1 infection

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