Violaceous Plaques & a Hidden Virus

Kaposi's sarcoma
A 50-year-old man presents with a new eye lesion and violaceous skin plaques. A positive HIV test reveals a classic opportunistic diagnosis.
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Purplish Plaques: A Hidden Clue

Leukemia cutis
A 65-year-old man presents with painful purplish plaques. Explore a case linking dermatological signs to a serious systemic hematological condition.
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A Curious Case of Skin Darkening

Vitamin B12 deficiency
A 59-year-old man presents with fatigue, a smooth tongue, and darkening skin on his palms and soles. Explore the differential diagnosis for these unusual signs.
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A Hidden Infection Unmasked

Larva currens from Strongyloides
A 64-year-old on steroids for cancer develops a rash and diarrhea. Explore the diagnosis of an opportunistic infection in an immunocompromised patient.
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A Case of ‘Wrinkled Tissue Paper’ Cells

Gaucher's disease
Explore the case of a 73-year-old man with fatigue, bone pain, and pancytopenia. What is the diagnosis behind the 'wrinkled tissue paper' cells?
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Unraveling a Sun-Sensitive Rash

Pellagra
A 48-year-old woman presents with diarrhea, weight loss, and a distinctive rash on sun-exposed areas. Explore this classic case of vitamin deficiency.
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The Telltale Eschar

Tetracycline
A 68-year-old woman in Japan presents with fever, a spreading petechial rash, and an eschar. Explore the diagnosis of this classic tick-borne illness.
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A Curious Case of Raindrop Skin

Arsenic toxicity
A 34-year-old woman develops raindrop-like skin changes on her chest and back. Her neighbors, who share a well, have similar symptoms. What is the cause?
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The Price of an Unproven Cure

Chelation Therapy
A 25-year-old man develops severe anemia, fatigue, and cough after using a folk remedy. Explore this case of an unexpected and dangerous poisoning.
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Fever & Jaundice After a Swim

Leptospirosis
An 18-year-old man develops fever, jaundice, and acute kidney injury after falling into a canal. Explore the diagnosis for this classic presentation.
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