A Persistent, Draining Neck Lump

Tuberculosis
A patient presents with persistent submandibular lymphadenopathy with skin drainage. Delve into the differential diagnosis and see why scrofuloderma was confirmed.
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Skin Clues to a Prostate Infection

Blastomyces dermatitidis
A patient presents with prostatitis and unusual skin lesions. Explore the differential diagnosis for systemic fungal infections that can manifest in the skin and GU tract.
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Blue Gums and a Bellyache

Lead poisoning
A patient presents with abdominal pain. A physical exam reveals a strange blue line on the gums. What is the underlying diagnosis? Explore this classic case.
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Unusual Lymphocytes & Splenomegaly

Hairy-cell leukemia
Explore a case of an indolent B-cell lymphoma presenting with cytopenias, massive splenomegaly, and distinctive abnormal lymphocytes. Learn about its diagnosis.
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Fever After an Insect Bite

Trypanosomiasis
A patient presents with fever and a chancre after a tsetse fly bite. Explore the diagnosis and management of this life-threatening parasitic infection.
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Fever, Rash & Swollen Glands

Rubella
A case of fever, sore throat, and suboccipital lymphadenopathy. Learn the key features to differentiate between common viral exanthems.
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More Than Just a Sore Throat

Syphilis
A patient presents with a common sore throat, but a facial lesion biopsy reveals an unexpected cause. Explore this case of a great masquerader.
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The Case of the Bull Neck

Diphtheria
Explore the diagnosis for a sick patient presenting with a bull neck, tachycardia, and a positive throat culture. Learn about key features of this infection.
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A Puzzling Palatal Mass

Syphilitic gumma
A patient presents with a large, often ulcerating mass on the tongue or hard palate. Explore the differential diagnosis and management of this rare oral lesion.
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A Tale of Two Dislocated Lenses

Marfan's syndrome
A 31-year-old woman presents with gradual bilateral vision loss. Imaging reveals posterior lens dislocation. What is the underlying systemic diagnosis?
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