A 2-Year Knee Swelling Mystery

Actinomycosis
A man has 2 years of left knee swelling and sinus tracts after a motorcycle accident. Explore the differential diagnosis for chronic cutaneous infections.
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A Case of Thirst, Oral Pain & Bone Lesions

Langerhans'-cell histiocytosis
Explore the differential diagnosis for a patient with oral pain, lytic bone lesions, excessive thirst, and urinary frequency. What connects these signs?
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Headache, Syncope, & Muscle Gain?

Cysticercosis
A 23-year-old woman presents with headache, syncope, and unusual muscle hypertrophy. Explore the diagnostic journey of this puzzling parasitic infection.
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Intermittent Fever, Unusual Smear

Plamodium vivax
An Eritrean man with a 3-year history of fevers and anemia presents with a strange finding on his blood smear. Can you identify the causative organism?
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Dull, Aching Nipple Pain in a Man

Mondor's disease
A 53-year-old man presents with dull, aching pain in his right nipple. Explore the differential diagnosis and management of this rare but benign condition.
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Auer Rods in Bone Marrow

Acute promyelocytic leukemia (APL)
A 69-year-old man has progressive neutropenia and anemia. A bone marrow aspirate reveals prominent Auer rods. What is the underlying hematological diagnosis?
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A Dangerous Rash During Chemo

Ecthyma gangrenosum
A 21-year-old with AML on chemotherapy develops a rapidly progressing skin lesion and fever. What is the diagnosis for this life-threatening condition?
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The Mystery of the Raindrop Skull

Multiple myeloma
A 46-year-old man presents with fatigue, weight loss, back pain, and hypercalcemia. Radiographs reveal a 'raindrop skull.' What's the diagnosis?
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A Risky Seafood Meal

Vibrio vulnificus
A 71-year-old man with diabetes develops fever, hand pain, and hemorrhagic bullae after eating raw seafood. Explore this rapidly progressing infection.
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A Sign on the Fingernails

Chemotherapy
Discover why a man undergoing cancer treatment developed strange white lines on his fingernails. What's the underlying cause of these nail changes?
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