A Dangerous Drug Interaction

Ergotism
A 24-year-old on HIV therapy develops severe leg pain after taking migraine medication. Explore a critical drug-drug interaction leading to limb ischemia.
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A Curious Case of Long Eyelashes

EGFR inhibition
A 53-year-old woman on treatment for appendiceal cancer develops unusually long eyelashes (trichomegaly). Explore the surprising cause of this side effect.
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A Concerning Palatal Ulcer

Extranodal natural killer T-cell lymphoma
A 50-year-old woman with a 3-year history of nasal obstruction presents with a new painless palatal ulcer and a swollen lip. What could be the diagnosis?
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A Curious Case of Leg Swelling

Echinococcal cysts
A 35-year-old man presents with a 6-month history of right leg swelling. Explore the diagnostic journey from physical exam and imaging to the final diagnosis.
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Bone Marrow Clues in Sickle Cell Anemia

Hemophagocytosis of sickle cells
A 60-year-old man with sickle cell disease presents with severe anemia. Explore the diagnostic significance of bone marrow findings in this challenging case.
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A Mysterious Pain After Chemo

Bone marrow necrosis
A 56-year-old man with acute leukemia develops severe back pain after chemo. Explore the differential diagnosis for this painful hematologic complication.
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Fever & Rash: An HIV Co-Infection

Talaromyces marneffei
Explore the case of a 31-year-old man with HIV presenting with fever, papular rash, and weight loss. What is the diagnosis for this dimorphic fungus?
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A Puzzling Rash on Palms & Soles

Syphilis
A 30-year-old man with HIV presents with a unique rash on his hands, feet, and face. Explore the diagnosis and management of this classic clinical case.
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Fever & Brain Lesions in the Immunocompromised

Nocardiosis
An 80-year-old man with multiple myeloma presents with fever, confusion, and ring-enhancing brain lesions. What's the diagnosis for these CNS findings?
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When Swollen Gums Signal Systemic Disease

Leukemic infiltration of the gingiva
A 48-year-old woman presents with fatigue and painful, swollen gums. Explore the differential diagnosis for this unusual presentation and its link to hematology.
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