A 3-year-old presents with dark urine, jaundice, and new anemia after a URI. Explore the diagnosis of a post-infectious Hemolytic Anemia.
A 3-year-old girl presented to the emergency department with a 1-day history of dark urine and jaundice after the development of an upper respiratory tract infection 1 week earlier. The physical examination was notable for pharyngeal erythema and exudates, conjunctival pallor, and scleral icterus. There was no hepatosplenomegaly, rash, or acrocyanosis. Laboratory studies showed a new anemia and findings consistent with hemolysis. A direct antiglobulin test was positive for C3d and weakly positive for IgG. A subsequent peripheral blood smear is shown. What is the most likely diagnosis?
What is the most likely diagnosis?
Autoimmune Hemolytic Anemia, Cold agglutinin syndrome, Hemolysis, Jaundice, Pediatrics
