A Gassy Gallbladder

Emphysematous cholecystitis
Discover the diagnosis for a patient with RUQ pain where imaging shows a gas-filled gallbladder. This rare and severe condition requires prompt action.
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Skin Signs of a Deeper Problem

Endocarditis
Discover how splinter hemorrhages under the fingernails and tiny skin petechiae can signal a serious systemic infection. Learn the key diagnostic clues.
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When Blood Lipids Cloud the View

Lipemia retinalis
Discover a rare ocular condition where high triglyceride levels cause retinal vessels to appear creamy or white. Learn about its diagnosis and systemic implications.
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A Neck Mass and Jaundice: What’s the Link?

Peripancreatic malignancy
Explore a clinical case of a patient presenting with jaundice and an enlarging neck mass. Learn how abdominal cancers can lead to supraclavicular metastasis.
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Chest Pain & a Widened Mediastinum

Ascending aortic aneurysm
A patient presents with chest pain. A chest radiograph reveals a widened mediastinum. Explore the differential diagnosis and key investigations for this finding.
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When Kidneys Fail: A Vascular Cause

Wegener's granulomatosis
A patient presents with hypertension, proteinuria, and acute renal failure. Explore the differential diagnosis for this classic triad and discover the underlying cause.
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Skin Thickening After Kidney Failure

Nephrogenic fibrosing dermopathy
A patient with renal failure develops progressive skin thickening. Explore the link between this rare dermatological condition and contrast agents in imaging.
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Mysterious White Lines on the Nails

Chemotherapy treatment
Discover the clinical significance of smooth white bands on the nails. Learn about a key nail finding linked to metabolic stress and systemic conditions.
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A Foot That Changes Color

Arterial insufficiency
A patient presents with a 10-day history of left foot discoloration that resolves with elevation. Explore the differential diagnosis and key clinical signs.
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A Puzzling Case of Oral Papules

Herpetic glossitis
A clinical case challenge: A patient presents with multiple well-defined white papules on the tongue, each with a central punctum. What is the diagnosis?
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