Anemia and an Unsteady Gait

Romberg's sign
Explore the case of a 76-year-old woman with pernicious anemia presenting with neurological signs, including sensory loss and gait instability. What is the key sign?
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Hidden Clues in a Monocyte

Histoplasma capsulatum
An immunodeficient man presents with fever, night sweats, and weight loss. His blood smear reveals intracellular yeast-like organisms. What's the diagnosis?
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Dark Lines on Nails: A Drug Link?

Zidovudine
Longitudinal melanonychia, or dark lines on the nails, can be a sign of a medication side effect. Discover the drugs commonly associated with this finding.
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Pigmented Genital Papules

Bowenoid papulosis
Explore a case of hyperpigmented genital papules linked to HPV. Learn about the histologic overlap with SCC in situ and the key diagnostic features.
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Gas in the Bowel Wall?

Pneumatosis cystoides coli
Explore a case of submucosal cysts in the colon. Learn about this rare condition, its presentation from asymptomatic to obstruction, and diagnostic clues.
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The Migrating Rash in Diabetes

Necrolytic migratory erythema
Explore a case of a patient with diabetes and a distinctive annular rash. Discover how this skin condition led to the diagnosis of a rare pancreatic tumor.
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Bone Changes & Pulmonary HTN

Beta-thalassemia
A medical case exploring the link between bony medullary expansion, extramedullary hematopoiesis, and the development of pulmonary hypertension. What's the diagnosis?
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The Buffalo Hump Mystery

Lipodystrophy
Explore the diagnosis for a dorsocervical fat pad in an otherwise lean patient. Learn about the causes and implications of abnormal fat distribution.
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A Curious Case of Crusted Plaques

Ostraceous psoriasis
Explore a dermatology case of sharply demarcated, erythematous plaques with limpet-like scales and crust. Learn the diagnosis for these unusual skin lesions.
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The Blueberry Muffin Baby

Congenital cytomegalovirus infection
A premature baby girl presents with anemia, thrombocytopenia, and a distinct skin rash. Explore the differential diagnosis for these concerning findings.
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