An Ophthalmic Clue to a Systemic Disease

Von Hippel-Lindau disease
An 18-year-old presents with right eye visual loss. Ophthalmoscopy reveals a tumor. What systemic condition could be the underlying cause?
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Beyond a Simple Toothache

Ludwig's angina
A simple toothache escalates into a life-threatening neck swelling. Understand the signs of this rapidly progressing infection that can compromise the airway.
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Where Did the Thyroid Go?

Ectopic thyroid
A case of subclinical hypothyroidism reveals neck nodules but no thyroid gland in its normal position. Explore this rare cause of thyroid dysfunction.
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What’s Biting in Cameroon?

Chrysops fly
A teen from Cameroon has a high parasite load and 17% eosinophilia. Learn about the vector responsible for transmitting Loa loa and its clinical presentation.
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A Suspicious Streak Under the Nail

Melanoma
Discover the significance of a dark streak under a nail. Learn about Hutchinson's sign and why this clinical finding requires urgent medical evaluation.
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Post-CABG Renal Failure Mystery

Cholesterol crystals
A patient develops kidney failure weeks after coronary bypass surgery. Discover the crucial finding on renal biopsy that reveals the unexpected diagnosis.
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An Unusual Cause of a Red Eye

Carotid cavernous sinus fistula
A patient presents with chemosis and conjunctival injection. CT shows a dilated superior ophthalmic vein. What is the underlying vascular diagnosis?
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Annular Rash & Anesthetic Skin

Tuberculoid leprosy
Explore a case of a patient with large, annular, hypopigmented macules. Learn how anesthetic skin and key histological findings lead to a specific diagnosis.
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A Painful, Rope-Like Cord on the Leg

Superficial thrombophlebitis
A patient presents with a tender, red, rope-like cord on the leg. Learn about the diagnosis and management of this common vascular condition.
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When Ears Turn to Stone

Adrenal insufficiency
Discover why calcification of the auricular cartilages, a rare physical finding, can be a crucial clue to a serious underlying systemic condition.
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