The Man with the ‘Horse Collar’ Neck

Alcohol dependency
Explore a case of diffuse, nonencapsulated fatty deposits. Learn about the diagnosis of Madelung's disease and the key historical factor associated with it.
Read more

Pain Out of Proportion

Mesenteric ischemia
A patient presents with a lethal abdominal condition. CT reveals SMA occlusion and bowel gas. Learn about this critical diagnosis and its grim prognosis.
Read more

A Chilling Vascular Puzzle

Waldenstrom's macroglobulinemia
A patient presents with progressive ischemic injury of the fingers and toes. Explore a case of hyperviscosity and cryoglobulinemic vasculitis.
Read more

A Calcified Surprise in the Abdomen

Splenic cyst
A patient presents with a large, circular calcified lesion on an abdominal film. Explore the diagnosis, imaging findings, and link to a remote trauma history.
Read more

When Papules Signal Danger

Calcitonin
A patient presents with flesh-colored papules on the face. Learn how these skin findings can point to a serious underlying endocrine condition like MEN-2B.
Read more

A Rash Under Black Light

Erythrasma
A patient presents with a rash. See how ultraviolet A light from a Wood's lamp, revealing a coral-red fluorescence, leads to a definitive diagnosis.
Read more

An Unvaccinated Teen’s Vesicular Rash

Varicella
An unvaccinated adolescent presents with fever and a classic, extensive pruritic vesicular rash. Can you identify the common viral illness behind these symptoms?
Read more

A Painful, Discolored Lower Leg

Ischemic gangrene
A patient with diabetes presents with a 4-month history of painful, progressive gangrene of the right leg. Explore the diagnosis based on a very low ABI.
Read more

Unraveling a Puzzling Palmar Rash

Treponema pallidum
A patient presents with a two-week history of nonpruritic, scaly, erythematous plaques on the palms and soles. Explore the differential diagnosis and management.
Read more

When Facial Papules Signal Systemic Disease

Tuberous sclerosis
A clinical case of yellow-orange facial papules on the nose and cheeks, hinting at an underlying autosomal dominant genetic disorder. What is the diagnosis?
Read more