A Tale of Two Limbs

Explore the clinical puzzle of differential cyanosis and clubbing. Learn why a patient might show signs of low oxygen in their feet but not their hands.
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The Sunburn-Like Rash

Explore the causes of a symmetric, scaly, sunburn-like rash. Learn how a specific dietary deficiency can lead to a distinctive photosensitive dermatitis.
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An X-ray of Hardened Skin

A radiograph of the right arm reveals calcinosis cutis. Explore the differential diagnosis for this finding and discover the underlying systemic condition.
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That Pesky Scalp and Face Rash

Explore a chronic inflammatory skin condition causing scaling and red patches on the scalp, face, and chest. Learn its features and diagnosis.
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Not Jaundice: A Puzzling Discoloration

Discover the cause of yellow skin discoloration on the palms and soles when jaundice is ruled out. Learn about the link between skin changes and systemic disease.
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Hypercalcemia & Low PTH: A Diagnostic Dilemma

Explore the differential diagnosis for a patient presenting with hypercalcemia, suppressed PTH, and bilateral hilar lymphadenopathy. A classic clinical puzzle.
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A Mysterious Bleeding Umbilical Nodule

A woman with a history of dysmenorrhea presents with an intermittently bleeding umbilical nodule. Explore the differential diagnosis for this rare condition.
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A Hairy Situation & A Viral Link

A patient with chronic Hepatitis C develops facial hair and a photosensitive rash. Explore the diagnosis confirmed by uroporphyrinuria. What's the link?
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A Bluish Bump in the Mouth

A patient presents with a nontender, smooth-walled, translucent, bluish mass on the tongue. Learn about the diagnosis and management of this common oral lesion.
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Chest X-Ray Mystery

A patient with cirrhosis undergoes repeated thoracentesis. A chest radiograph reveals a collapsed lung and a distinct air-liquid level. What's the diagnosis?
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