A Post-Transplant Hand Puzzle

Pseudoclubbing
A 36-year-old man with a history of renal transplant and parathyroidectomy presents with changes in his hands. Explore the differential diagnosis and key features.
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A Dark Sign in the Skin Folds

Insulin resistance
Discover the common endocrine condition linked to acanthosis nigricans, the velvety, dark skin patches in body folds. Learn its significance and management.
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The Crystal Culprit of Joint Destruction

Gout
Challenge your diagnostic skills with this case of severe joint deformity. Learn about the pathophysiology and management of crystalline arthropathies.
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Fever and a Telltale Rash

Measles
A 16-year-old boy presents with malaise and fever. Examination reveals pathognomonic white spots on his buccal mucosa. Can you identify the diagnosis?
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A Wriggly Finding on Colonoscopy

Enterobius vermicularis
A 55-year-old man presents with lower abdominal pain. A colonoscopy reveals mobile 1-cm worms in the cecum. Explore the diagnosis and management.
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A Child’s Silent Ear Problem

Cholesteatoma
A 5-year-old girl fails a school hearing screening. Examination reveals a white mass behind an intact left tympanic membrane. What's the diagnosis?
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What Are These Colon Opacities?

Ingestion of a heavy metal
An abdominal radiograph reveals multiple punctate opacities throughout the colon. Discover the differential diagnosis and identify the most likely cause.
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S4 Gallop, High JVP: What’s Next?

Congestive heart failure
A patient presents with an S4 gallop, elevated JVP, and bilateral pitting edema. Uncover the likely diagnosis behind these classic signs of cardiac dysfunction.
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Abdominal Pain & a Blood Smear Clue

Chronic lead poisoning
A 61-year-old man presents with abdominal pain. A peripheral blood smear reveals basophilic stippling. What's the underlying cause?
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A Curious Parotid Complication

Frey's syndrome
Explore the causes of gustatory sweating after parotid gland surgery. Learn about the diagnosis and management of this unique post-operative complication.
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