Clues on the Knuckles

Bulimia nervosa
Erythematous plaques on the knuckles can be more than just calluses. Explore the link between these dermatological findings and a serious disorder.
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A Surprising Fix for Prolapse

Sugar
Discover an unconventional but effective method for reducing tissue edema in prolapses. Learn how a common household item can facilitate non-surgical reduction.
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Hardened Skin, A Deeper Cause

Systemic sclerosis
A case of calcinosis cutis. Explore the differential diagnosis for skin calcifications and discover the underlying systemic autoimmune condition.
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A Vascular Detour

Thrombosis of the inferior vena cava
A case of chronic venous obstruction confirmed by CT imaging. Explore why superficial veins dilate to create a collateral pathway for blood return.
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A Rare Cause of Pneumatosis Intestinalis

Alpha-glucosidase inhibitor
An abdominal radiograph shows pneumatosis cystoides intestinalis. Discover which common diabetes medication group has been linked to this rare condition.
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The ‘Thumb Sign’ on a Neck X-ray

Epiglottitis
Discover the critical diagnosis behind the 'thumb sign' on a lateral neck radiograph. Learn why this finding in a patient with a sore throat is a medical emergency.
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An Agonizing Elbow

Monosodium urate
A patient presents with acute elbow pain. Polarized microscopy of a joint aspirate reveals key diagnostic crystals. What is the underlying condition?
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Firm, Yellow Scrotal Bumps

Scrotal calcinosis
A clinical case presenting with multiple painless, firm, yellowish nodules on the scrotum. Explore the differential diagnosis for this benign dermatological condition.
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Sweating, Weight Loss & a Neck Swelling

Graves' disease
A patient presents with diaphoresis, cachexia, and a diffusely enlarged thyroid. Explore the diagnostic process for this common endocrine disorder.
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Waxy Papules & Raccoon Eyes: What’s the Link?

Multiple myeloma
A patient presents with waxy papules and periorbital ecchymoses (raccoon eyes). Explore the diagnostic journey for this underlying systemic condition.
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