A Painful Nodule Under the Nail

A patient presents with a tender, keratotic, subungual nodule. Radiography reveals a cup-shaped erosion of the distal phalanx. What's the diagnosis?
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A Pancreatic Clue on the Skin

A patient presents with elevated lipase and pancreatitis. What could be the cause of their painful subcutaneous nodules? Explore this uncommon dermatologic sign.
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The Case of the Missing Knuckle

A patient presents with a missing fourth knuckle. Discover the rare genetic disorder behind this sign, its pathophysiology, and clinical implications.
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Thickened Skin, Hidden Danger

Explore the link between thickened skin on the palms and soles and an increased risk of esophageal cancer. Learn about this rare genetic syndrome.
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Decoding a Complex Gallium Scan

A gallium scan reveals widespread uptake in lymph nodes, lungs, and parotids. Explore the classic signs and differential diagnosis for this systemic condition.
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Fingers Changing Color in the Cold?

A patient presents with fingers that turn white and blue when exposed to cold. Explore the causes and management of this common vascular phenomenon.
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A Clue in the Clavicle

A patient presents with unintentional weight loss. A key finding on physical exam, a left supraclavicular lymph node, points towards a serious diagnosis.
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A Wriggling Cause of Obstruction

A child presents with acute intestinal obstruction. Explore this case of a rare surgical finding in the terminal ileum and its surprising infectious etiology.
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Unusual Lymphocytes & Splenomegaly

Explore a case of an indolent B-cell lymphoma presenting with cytopenias, massive splenomegaly, and distinctive abnormal lymphocytes. Learn about its diagnosis.
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