Mysterious Crystals in an RA Patient’s Elbow

Cholesterol
A patient with rheumatoid arthritis has an elbow effusion. Aspiration reveals unique rectangular, platelike crystals. What is the diagnosis?
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A Mass on the Tongue

Squamous-cell carcinoma
This case explores a 2 cm vegetative mass on the tongue with leukoplakia. Learn about the diagnostic approach, including biopsy, for such oral lesions.
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A Painful Lump Under the Jaw

Sclerosing sialadenitis
A patient reports weeks of submandibular pain, leading to a fine-needle aspiration. Explore the diagnosis of a firm, inflammatory salivary gland condition.
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An Eye-Opening Systemic Disease Clue

Rheumatoid arthritis
A case of corneal perforation with iris prolapse reveals a surprising underlying systemic autoimmune disease. Learn to recognize this critical sign.
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A Puzzling Umbilicated Papule

Cryptococcosis
A patient with a low CD4 count develops a new umbilicated facial papule. Explore the differential diagnosis for this opportunistic infection.
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Bilateral Fractures: A Deeper Look

Osteomalacia
Explore a case of bilateral femur fractures and osteopenia on a pelvic radiograph. Learn the key diagnostic features and differential diagnoses.
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Cerebral Calcification: An Unusual Clue

Celiac disease
Explore a case of cerebral calcification linked to folate malabsorption. Discover how a common gastrointestinal disorder can have surprising neurological signs.
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Vision Loss in Late Pregnancy

Preeclampsia
A 36-week pregnant woman presents with sudden vision loss. Discover the diagnosis linked to severe hypertension and grade 4 hypertensive retinopathy.
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A Scaly Rash on the Face

Tinea faciei
A patient presents with well-marginated, scaly lesions on the face. Learn about the diagnosis and management of this common dermatological condition.
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A Curious Lesion on the Finger

Metastasis
A 50-year-old woman presents with a firm lesion on her finger. Radiography reveals a lytic bone lesion. What is the underlying diagnosis?
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