Toenail Clues to a Hidden Diagnosis

Periungual fibroma
A 71-year-old man with chronic kidney disease presents with facial papules and unusual toenail lesions. Discover the underlying systemic diagnosis.
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A Deceptive Foot Lesion in the Elderly

Amelanotic melanoma
An 80-year-old man presents with a growing, ulcerated lesion on his foot. Explore the differential diagnosis for this challenging clinical presentation.
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An Incidental Iris Finding

Prominent iris collarette
A 37-year-old woman presents with allergic conjunctivitis, but a slit-lamp exam reveals an incidental and unusual finding on her iris. What is it?
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A Shocking Post-Ablation Collapse

Left ventricle
A 60-year-old man with atrial fibrillation presents with chest pain and collapse after a recent procedure. A CT scan reveals a shocking and rare finding.
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Auer Rods in Bone Marrow

Acute promyelocytic leukemia (APL)
A 69-year-old man has progressive neutropenia and anemia. A bone marrow aspirate reveals prominent Auer rods. What is the underlying hematological diagnosis?
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Swelling & Stomach Pain in a Child

Ménétrier's disease
A 5-year-old boy presents with nausea, vomiting, and periorbital edema. Explore a rare cause of protein-losing enteropathy in children.
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A Post-Angiogram Surprise

Iodide-associated sialadenitis
A 67-year-old man with cardiac and renal disease develops acute neck swelling, dysphagia, and hoarseness after a coronary angiogram. What's the diagnosis?
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An Old Cure’s Lasting Mark

Oleothorax
An 86-year-old with epigastric pain has a surprising chest x-ray. Discover a rare diagnosis linked to a historical treatment for tuberculosis.
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A Devastating Rash in an Immunocompromised Host

Strongyloides stercoralis
A 47-year-old man with dermatomyositis presents with a rash, abdominal pain, melena, and hemoptysis. Explore this complex case of hyperinfection.
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Fast-Growing Eyelid Lesion

Pyogenic granuloma
A 30-year-old man develops a rapidly growing lesion on his eyelid just weeks after a cyst ruptured. Explore the diagnosis for this benign vascular growth.
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