A Sudden, Swollen, and Cold Leg

An 81-year-old man presents with acute pain, swelling, and coldness in his left leg with an absent pulse. Explore this critical case of extensive thrombosis.
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A Rapid Neurologic Decline

A 54-year-old man presents with a 3-week history of cognitive decline, ataxia, and myoclonus. Explore the diagnosis of this rapidly fatal condition.
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Infant Vomiting & An Abdominal Clue

A 23-day-old male presents with increasing vomiting, dehydration, and a palpable abdominal mass. Explore this classic pediatric emergency case.
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A Puzzling Pox on the Cheek

An 11-year-old girl develops an antibiotic-resistant facial ulcer. Explore the diagnosis of a rare zoonotic infection transmitted by a common household pet.
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A Puzzling Case of Fever and a Pulsatile Hand

A 27-year-old presents with fever, weight loss, a heart murmur, and a rare ulnar artery aneurysm. Uncover the underlying systemic diagnosis.
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A Dangerous Rash During Chemo

A 21-year-old with AML on chemotherapy develops a rapidly progressing skin lesion and fever. What is the diagnosis for this life-threatening condition?
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A Chilling ECG Finding

A 76-year-old woman is found outdoors. Explore the classic ECG finding associated with hypothermia and its differential diagnoses. Test your knowledge.
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A Dizzying Case of Red Eyes

A case of a young woman with interstitial keratitis and vestibuloauditory dysfunction. Uncover the diagnosis and management of this rare inflammatory disorder.
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A Child’s Ulcer After a Trip Abroad

A 5-year-old girl develops nonhealing, ulcerative skin lesions on her legs after a trip to Sierra Leone. Explore the differential diagnosis.
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