A Bull’s-Eye in the Visual Field

Hydroxychloroquine toxicity
A 60-year-old woman with rheumatoid arthritis develops central blind spots. Explore the retinal findings and differential diagnosis for bull's-eye maculopathy.
Read more

The Forgotten Disease

Fusobacterium necrophorum
An 18-year-old presents with sore throat, fever, and chest pain. Imaging reveals pulmonary cavities and a jugular vein thrombus. What is the likely pathogen?
Read more

A Troublesome Tongue Lesion

Spindle-cell sarcoma
A 54-year-old man presents with a growing brown lesion on his tongue within a white patch, causing difficulty chewing. What is the diagnosis?
Read more

A Traveler’s Itchy Souvenir

Tungiasis
A 10-year-old girl develops itchy, painful papules with black dots on her feet after a trip to rural Brazil. Explore this case of a parasitic skin infestation.
Read more

A Case of Sweating, Headaches & Skin Folds

Acromegaly
A 37-year-old man presents with a 4-year history of excessive sweating, headaches, joint pain, and unusual skin folds on his scalp. Explore the diagnosis.
Read more

A Blind Eye’s Hidden Danger

Uveal melanoma
A 59-year-old woman with a history of blindness in one eye presents with pain, leading to the discovery of an orbital mass and widespread metastatic disease.
Read more

Skin Spots and a Twisted Bowel

Peutz–Jeghers syndrome
A 45-year-old man presents with acute abdominal pain. Discover how hyperpigmented spots on his lips and a family history lead to a rare genetic diagnosis.
Read more

Stuck on Pizza: A Case of Food Impaction

Eosinophilic esophagitis
Explore the case of a young man with difficulty swallowing and food impaction. Endoscopy shows fixed esophageal rings. What is the underlying diagnosis?
Read more

A Refractive Surprise: A 20-Year Vision Shift

Radial keratotomy
A 41-year-old woman experiences a hyperopic shift and worsening vision 20 years after a procedure. Explore the long-term effects of older refractive surgeries.
Read more

Puzzling Nodules Post-Transplant

Malakoplakia
A 53-year-old transplant recipient develops painless nodules on his scalp and perianal region. Discover the diagnosis behind these unusual skin lesions.
Read more