Air in the Spleen: A Diagnostic Puzzle

Gastrosplenic fistulization
A 56-year-old woman with LUQ abdominal pain and a history of NSAID use has a CT showing air in the spleen. Explore this rare and critical diagnosis.
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A Persistent Midline Neck Lump

Thyroglossal duct cyst
A 68-year-old woman presents with a 5-year history of neck swelling and new-onset dysphagia. Explore the differential diagnosis for a midline neck mass.
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Painful Hands & Breathing Trouble

Anti-MDA5 dermatomyositis
A 48-year-old man presents with painful hand ulcers and shortness of breath. Explore the diagnosis behind this rare but serious dermatological condition.
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An Unexpected Coronary Finding

IgG4-related disease arteritis
A 47-year-old man with a history of IgG4-related disease is found to have asymptomatic coronary artery aneurysms. What's the underlying pathology?
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A Chilling Case of Dizziness and Rash

Cold agglutinin disease
A 70-year-old woman develops dizziness and a purplish rash after a viral infection in cold weather. Explore this case of autoimmune hemolytic anemia.
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A Curious Case of Knee Pain

Synovial chondromatosis
A 46-year-old woman with a history of rheumatoid arthritis presents with worsening knee pain and walking difficulty. Discover the unusual diagnosis.
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A Rapidly Worsening Sore Throat

Epiglottitis
A 48-year-old man presents with a sore throat, fever, and progressive dyspnea. Explore this critical case of a life-threatening upper airway obstruction.
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HIV Patient with Headache & Tongue Lesion

Disseminated coccidioidomycosis
A 34-year-old man with HIV presents with headache, fever, confusion, and a large ulcerative tongue lesion. Explore this case of an opportunistic infection.
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Painless Neck Mass: What’s the Cause?

Tonsillar cancer
A 60-year-old man presents with a firm, painless neck mass and unilateral tonsil enlargement. Explore the diagnosis for this common clinical scenario.
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Anal Pruritus: Not Always Hemorrhoids

Enterobiasis
A 32-year-old woman presents with anal pruritus and bleeding. While hemorrhoids are suspected, the true cause is an unexpected parasitic infection.
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