Salt-and-Pepper Skin & Shortness of Breath

Diffuse cutaneous systemic sclerosis
A 68-year-old man presents with interstitial lung disease and unique 'salt-and-pepper' skin changes. Explore this rheumatology case and its diagnosis.
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A Colorful Clue in the Colon

Gastrointestinal amyloidosis
A 60-year-old woman with rheumatoid arthritis presents with diarrhea and nausea. Colonoscopy and biopsy reveal a surprising diagnosis. What could it be?
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A Young Woman’s Rash & Aches

Systemic lupus erythematosus
Explore the case of a 34-year-old woman with a persistent cheek rash and joint pain. Learn about the key diagnostic markers and treatment approaches.
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Hand Lesions in a Man with Hepatitis C

Porphyria cutanea tarda
A 65-year-old man with ESRD and hepatitis C presents with skin lesions on his hands and forearms and thick nails. Explore the differential diagnosis.
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A Puzzling Rash on Palms & Soles

Syphilis
A 30-year-old man with HIV presents with a unique rash on his hands, feet, and face. Explore the diagnosis and management of this classic clinical case.
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Mystery of the Lethargic Neonate

Infantile hepatic hemangiomas
A 16-day-old girl presents with lethargy, tachypnea, and hepatomegaly. Explore a case of hepatic lesions, cardiomegaly, and consumptive hypothyroidism.
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A Child’s Unexpected Rash

Amoxicillin rash in infectious mononucleosis
A child develops a widespread maculopapular rash after taking amoxicillin for pharyngitis. Explore the differential diagnosis and key investigations.
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What’s Bugging This Traveler?

Myiasis
A woman returns from travel with pruritic skin nodules unresponsive to antibiotics. Explore the differential diagnosis for a returning traveler's skin lesion.
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A Fall and Failing Sight

Intraocular lens dislocation
A 60-year-old man experiences decreased vision and eye pain after a fall. Explore the differential diagnosis and management of post-traumatic vision loss.
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White Tongue Lesion: A Warning?

Leukoplakia
A 40-year-old man with a history of smokeless tobacco use presents with a painless, white lesion on his tongue. What could this oral finding signify?
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