Pruritus and Pustules in Pregnancy

Atopic eruption of pregnancy
A 37-year-old woman at 30 weeks' gestation has a widespread, pruritic rash. Review the workup and diagnosis of common dermatoses in pregnancy.
Read more

When Tummy Troubles Turn Toxic

Bismuth Salicylate
An elderly woman's self-treatment for IBS leads to altered mental status and a mixed acid-base disorder. Discover the surprising over-the-counter cause.
Read more

Fever & Jaundice After a Swim

Leptospirosis
An 18-year-old man develops fever, jaundice, and acute kidney injury after falling into a canal. Explore the diagnosis for this classic presentation.
Read more

The ‘Filarial Dance’ in the Scrotum

Mosquito
A 26-year-old man presents with scrotal pain, swelling, and a strange finding on ultrasound. What parasitic infection could be the cause?
Read more

Velvety Plaques & Hidden Dangers

Malignant acanthosis nigricans
A 30-year-old presents with skin lesions. Learn how velvety plaques can be a critical paraneoplastic sign of an underlying malignancy, like gastric cancer.
Read more

A Rare Complication of Long-Term PD

Encapsulating peritoneal sclerosis
A 52-year-old woman on long-term peritoneal dialysis for ESKD presents with bloody dialysate. Explore the diagnosis based on abdominal CT and laparoscopy.
Read more

Platelet Count Conundrum

Pseudothrombocytosis due to red cell fragments
An ICU patient with severe burns has a platelet count of 930,000 on an automated analyzer, but a manual smear shows 115,000. What explains this?
Read more

A Winding Rash After IV Therapy

Serpentine supravenous hyperpigmentation
A 58-year-old woman with cancer develops a linear, hyperpigmented rash along the veins of her arms after IV therapy. What's the diagnosis?
Read more

Olive-Brown Pleural Fluid?

Bilirubin
A 77-year-old man with metastatic lung cancer develops dyspnea and an unusual olive-brown pleural effusion. What is the key diagnostic test?
Read more

What’s This Bleeding Lip Bump?

Pyogenic granuloma
A 45-year-old woman presents with a painless, rapidly growing, friable lesion on her upper lip. Explore the differential diagnosis for this presentation.
Read more