Jaundice & Anemia After a Cold

Cold agglutinin syndrome
A 3-year-old presents with dark urine, jaundice, and new anemia after a URI. Explore the diagnosis of a post-infectious hemolytic anemia.
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When Kidneys Weaken the Knees

Quadriceps tendon ruptures
A 38-year-old man with end-stage renal disease presents with progressive difficulty walking after a minor injury. What's the underlying orthopedic issue?
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Puzzling Pneumonia & Eosinophils

Chronic eosinophilic pneumonia
A 54-year-old woman with asthma presents with a productive cough, dyspnea, and weight loss. Labs show high eosinophils, and CT shows peripheral consolidation.
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When Back Pain Blurs Your Vision

Intravitreal antimicrobial injections
A 44-year-old man with diabetes and ESKD presents with eye pain, vision loss, and back pain. Explore the diagnosis of this vision-threatening condition.
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Beyond the Kidney: A Hidden Danger

Chest imaging
A 60-year-old woman presents with kidney failure. Diagnosis: anti-GBM disease. What critical test is needed to check for involvement beyond the kidneys?
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Rash & Fever: Early HIV Clues

HIV nucleic acid test
A 26-year-old man presents with a rash, sore throat, and fever after recent condomless sex. Explore the diagnosis of acute HIV and its earliest detection.
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A Case of Cardiac Constriction

Constrictive Pericarditis
A 69-year-old woman with asbestos exposure presents with dyspnea. Explore the diagnosis behind ventricular interdependence and the 'square root' sign.
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A Puzzling Pruritic Rash

Reactive perforating collagenosis
An 83-year-old woman with diabetes presents with a chronic, itchy rash on her back. Discover the diagnosis behind these unique crateriform lesions.
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When Skin Hardens: A Complex Case

Scleromyxedema
A 53-year-old man presents with a waxy, itchy rash, skin thickening, and dysphagia. Explore a rare diagnosis linked to monoclonal gammopathy.
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An Itchy, Streaky Back Rash

Shiitake mushrooms
A 72-year-old man develops an itchy, flagellate rash on his back. What common food item could be the surprising culprit? Explore this case of dermatitis.
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