A Telltale Tongue in HIV

Secondary syphilis
A 29-year-old man with HIV presents with painful tongue lesions. Explore the differential diagnosis for oral changes in immunocompromised patients.
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Not Your Typical Heart Attack

Dissection
A healthy 32-year-old woman has severe chest pain. ECG shows a heart attack, but angiography reveals an abrupt arterial change. What's the cause?
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When Sunshine and Plants Don’t Mix

Phytophotodermatitis
A man develops a painful, burning rash with blisters on his hands after a day outdoors. Discover the surprising cause of this phototoxic skin reaction.
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When Arm Exercise Steals from the Heart

Coronary-Subclavian Steal Syndrome
Explore a case of angina triggered by arm exercise in a post-CABG patient. Discover how subclavian artery occlusion can "steal" blood from the heart.
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A Curious Case of Darier’s Sign

Solitary Mastocytoma
A 10-month-old girl presents with a growing, itchy neck lesion. Stroking the lesion causes it to swell and redden. What is the likely diagnosis?
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Skin Lesions & A Fungal Clue

Malassezia species
A 30-year-old man has a 6-month history of depressed, red skin lesions on his back. Explore the diagnosis behind this unusual fungal presentation.
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Radiograph Signs in Acute Dyspnea

Pulmonary embolism
A 90-year-old man with a-fib and dementia presents with sudden dyspnea. Explore classic chest radiograph findings that point to a life-threatening diagnosis.
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Blue-Gray Macules After Melanoma

Tumoral melanosis
An 84-year-old on immunotherapy for melanoma develops new blue-gray macules. Are they metastases or something else? Learn about this diagnostic challenge.
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The Hidden Cause of a Child’s Poor Growth

Trichuris trichiura (whipworm)
Explore a pediatric case of a toddler with a 6-month history of diarrhea, anemia, and failure to thrive, leading to an unexpected endoscopic finding.
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The Curious Case of Slate-Gray Skin

Argyria
An 84-year-old man presents with a 5-year history of progressive, diffuse slate-gray skin pigmentation. Explore the diagnostic workup for this rare condition.
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