A 22-year-old man presents with a chronic red, Scaly Rash. Biopsy reveals acantholysis and intercellular IgG deposits. What is the diagnosis?
A 22-year-old man presented to the dermatology clinic with a 1-year history of a red, scaly rash on his face and body. On physical examination, widespread erythroderma with overlying erosions, scaling, and crusting was observed. The oral mucosa was spared. A skin biopsy from the back showed superficial acantholysis (the loss of adhesion between keratinocytes). Direct immunofluorescence of the biopsy specimen showed intercellular IgG antibodies against desmoglein-1 in the superficial layers of the epidermis. What is the most likely diagnosis?
