Hand Lesions in a Man with Hepatitis C

A 65-year-old man with ESRD and hepatitis C presents with skin lesions on his hands and forearms and thick nails. Explore the Differential Diagnosis.

Porphyria cutanea tarda


A 65-year-old man presented with six months of worsening lesions on his hands and forearms as well as fingernail thickening. His medical history included end-stage renal disease and untreated hepatitis C virus infection. What is the diagnosis?

What is the most likely diagnosis?

Buruli ulcers
Peripheral vascular disease
Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis
Porphyria cutanea tarda
Blastomycosis

Dermatology, Hepatitis C, Porphyria cutanea tarda, Skin Manifestations, Uroporphyrins

Leave a Comment