Salt-and-Pepper Skin & Shortness of Breath

A 68-year-old man presents with interstitial Lung disease and unique ‘salt-and-pepper’ skin changes. Explore this rheumatology case and its diagnosis.

Diffuse cutaneous systemic sclerosis


Examination of a 68-year-old man with interstitial lung disease was notable for skin changes characterized by alternating areas of hypopigmentation and hyperpigmentation on sclerotic skin. What is the most likely diagnosis?

What is the most likely diagnosis?

Amyopathic dermatomyositis
Leprosy
Diffuse cutaneous systemic sclerosis
Subacute cutaneous lupus erythematosus
Adult-onset Still’s disease

Anti-Scl-70, Diffuse cutaneous systemic sclerosis, Interstitial Lung Disease, Salt-and-pepper skin, Scleroderma

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