Vision Loss and Headaches in SLE

A 17-year-old with SLE presents with acute Vision Loss and chronic headaches. Explore the diagnostic process behind this complex ophthalmologic emergency.

Antiphospholipid syndrome


A 17-year-old girl with systemic lupus erythematosus presented to the ophthalmology clinic with a 2-day history of decreased vision in her right eye and a 6-month history of intermittent headaches. She stopped treatment with methylprednisolone and hydroxychloroquine 2 years ago. Examination of the fundus of the right eye is as shown. What is the diagnosis?

What is the most likely diagnosis?

Antiphospholipid syndrome
Retinal toxoplasmosis
Lupus retinal vasculitis
Susac’s syndrome
Hydroxychloroquine-induced maculopathy

Antiphospholipid syndrome, Lupus anticoagulant, Retinal artery occlusion, Systemic Lupus Erythematosus, Thrombosis

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