A 60-year-old man with sickle cell disease presents with severe Anemia. Explore the diagnostic significance of bone marrow findings in this challenging case.
A 60-year-old man presented to the hematology clinic with fatigue and dyspnea on exertion. He had a history of sickle cell disease with hemoglobin genotype SS. Laboratory studies showed a hemoglobin level of 4 g per deciliter. Light microscopy of a bone marrow biopsy specimen is as shown. What is the diagnosis?
What is the most likely diagnosis?
Bone marrow biopsy, Hemophagocytosis of sickle cells, Histiocyte, Severe Anemia, Sickle Cell Disease
