The Ominous Sign of Silver Stool

A 69-year-old woman presents with Dizziness, jaundice, and the rare finding of silver stool. Explore the diagnostic journey for this unusual presentation.

Metastatic colon cancer


A 69-year-old woman presented to the emergency room after experiencing 2 weeks of dizziness. On physical exam she appeared jaundiced, and had hepatomegaly and generalized abdominal tenderness. Rectal exam showed silver-colored stool. She had a hemoglobin level of 7.5 g per deciliter (reference range, 11.0 to 14.5), an elevated total bilirubin level, and an elevated alkaline phosphatase level. What is the diagnosis?

What is the most likely diagnosis?

Upper gastrointestinal bleed
Metastatic colon cancer
Heavy-metal toxicity
Liver cirrhosis
Dubin-Johnson syndrome

Gastrointestinal bleeding, Hepatomegaly, Metastatic colon cancer, Obstructive jaundice, Silver stool

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