Painful Hands & Breathing Trouble

A 48-year-old man presents with painful Hand ulcers and shortness of breath. Explore the diagnosis behind this rare but serious dermatological condition.

Anti-MDA5 dermatomyositis


A 48-year-old man presented to the dermatology clinic with a 6-month history of painful hand ulcerations and shortness of breath. He has no muscle weakness or arthritis. What is the diagnosis?

What is the most likely diagnosis?

CREST syndrome
Anti-MDA5 dermatomyositis
Pyoderma gangrenosum
Cutaneous polyarteritis nodosa
Behcet’s disease

Anti-MDA5 dermatomyositis, Dermatomyositis, Gottron’s papules, Interstitial Lung Disease, Vasculopathy

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