A Dark Turn in Antibiotic Therapy

A 55-year-old woman with a crush injury develops a polymicrobial infection. Post-antibiotic treatment, she presents with nausea and Tongue discoloration.

Tetracyclines


A 55-year-old woman was admitted to hospital after sustaining a severe crush injury to both legs in a motor vehicle accident. A polymicrobial wound infection developed and she received antibiotic treatment. Black discoloration of her tongue was observed within 1 week of starting treatment, and the patient reported nausea and a bad taste in her mouth. Which class of antibiotic can lead to this presentation?

What is the most likely diagnosis?

Tetracyclines
Penicillins
Macrolides
Fluoroquinolones
Sulfonamides

Adverse Drug Reaction, Antibiotics, Black Hairy Tongue, Minocycline, Tetracyclines

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