A Dangerous Rash During Chemo

A 21-year-old with AML on Chemotherapy develops a rapidly progressing skin lesion and fever. What is the diagnosis for this life-threatening condition?

Ecthyma gangrenosum


A 21-year-old woman with acute myeloid leukemia who was undergoing induction chemotherapy presented with a lesion on her left knee that had developed 5 days after initiation of therapy. Physical examination revealed a hemorrhagic patch with an erythematous border that progressed rapidly into a violaceous pustule. The patient developed a fever, and laboratory findings were notable for pancytopenia. Blood and wound cultures grew gram-negative rod-shaped bacterium. What is the diagnosis?

What is the most likely diagnosis?

Cyroglobulinemia
Necrotizing fasciitis
Polyarteritis nodosa
Ecthyma gangrenosum
Pyoderma gangrenosum

Ecthyma gangrenosum, Immunocompromised Host, Neutropenia, Pseudomonas aeruginosa, Sepsis

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