A Puzzling Pox on the Cheek

An 11-year-old girl develops an antibiotic-resistant facial ulcer. Explore the diagnosis of a rare zoonotic infection transmitted by a common household pet.

Cats


An 11-year-old girl presented to the hospital with 3-week history of an an ulcerated lesion on her cheek, unresponsive to a course of antibiotics. PCR testing of a swab specimen from the lesion was positive for orthopoxvirus DNA and cowpox virus-specific oligonucleotides. Exposure to what animal is the likely route of transmission?

What is the most likely diagnosis?

Cows
Sheep
Chickens
Rabbits
Cats

Cats, Cowpox virus, Dermatology, Orthopoxvirus, Zoonosis

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