A Puzzling Case of Darkening Skin

Explore a case of a patient with generalized weakness and progressive, widespread skin discoloration. What is the rare, underlying diagnosis? Learn more.

Diffuse melanosis cutis


What is the most likely diagnosis in a patient with generalized weakness and this finding?

What is the most likely diagnosis?

Lichen planus pigmentosus
Smoker’s melanosis
Cushing’s disease
Diffuse melanosis cutis
Hemochromatosis

Diffuse melanosis cutis, Hyperpigmentation, Malignant melanoma, Oncology, Paraneoplastic syndrome

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