When Swollen Gums Signal Systemic Disease

A 48-year-old woman presents with fatigue and painful, swollen gums. Explore the Differential Diagnosis for this unusual presentation and its link to hematology.

Leukemic infiltration of the gingiva


A 48-year-old woman presented to the emergency department with a 1-week history of fatigue and painful, swollen gums. On examination, she was febrile and tachycardic with a well-demarcated region of gingival infiltration and whitening and submandibular lymphadenopathy. A white-cell count was 225,000 per cubic millimeter. What is the diagnosis?

What is the most likely diagnosis?

Gingival candidiasis
Leukemic infiltration of the gingiva
Oral lichen planus
Proliferative verrucous leukoplakia
White sponge nevus

Acute Monocytic Leukemia, Acute Myeloid Leukemia, Gingival Hyperplasia, Hematology, Leukemic infiltration of the gingiva

Leave a Comment