A Case of Progressive Eye Swelling

A 67-year-old man presents with a 1-year history of bilateral eye swelling, proptosis, and recent Blurry Vision. Explore this diagnostic challenge.

IgG4-related ophthalmic disease


A 67-year-old man presented with a 1-year history of bilateral eye swelling and right eye protrusion and a 2-week history of blurry vision. There was no swelling of the parotid or submandibular glands. MRI of the orbits showed bilateral lacrimal gland and lateral rectus muscle swelling as well as mass lesions surrounding the optic nerves. He was initiated on daily prednisone with improvement in his symptoms. What is the diagnosis?

What is the most likely diagnosis?

IgG4-related ophthalmic disease
Non-Hodgkin’s lymphoma
Sjogren’s syndrome
Tuberculosis-related dacryoadenitis
Thyroid eye disease

Autoimmune Disease, Corticosteroids, IgG4-related ophthalmic disease, Lacrimal Gland Swelling, Proptosis

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