A Case of Thirst, Oral Pain & Bone Lesions

Explore the Differential Diagnosis for a patient with oral pain, lytic bone lesions, excessive thirst, and urinary frequency. What connects these signs?

Langerhans'-cell histiocytosis


What is the most likely diagnosis in a man with oral pain, urinary frequency, thirst, and these radiographic findings?

What is the most likely diagnosis?

Vitamin D excess
Scurvy
Langerhans’-cell histiocytosis
Paget’s disease of bone
Metastatic prostate cancer

Dendritic Cells, Diabetes Insipidus, Histiocytosis, Langerhans’-cell histiocytosis, Lytic Bone Lesions

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