A Child’s Fever and Painful Blisters

A 7-year-old girl develops fever and widespread painful blisters after a course of Penicillin. Explore the diagnostic process for this rare skin condition.

Neutrophilic dermatosis


A 7-year-old girl presented with a 2-week history of fever and painful blisters throughout the body. She completed a course of penicillin for tonsillitis two weeks earlier. Physical examination showed multiple bullae on her extremities and lesions on her lips. Five days after admission, she developed a new skin ulcer on the right hand at the site of an intravenous cannula. What is the diagnosis?

What is the most likely diagnosis?

Neutrophilic dermatosis
Dermatitis herpetiformis
Blastomyces dermatitidis
Pemphigus vulgaris
Leukocytoclastic vasculitis

Dermatology, Neutrophilic Dermatosis, Pathergy, Pediatrics, Sweet’s syndrome

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