An 82-year-old man presents with weakness and altered mental status. Despite treatment for Meningitis, he rapidly declines. What is this rare, fatal brain infection?
An 82-year-old man presented to the emergency department with a 2-week history of generalized weakness and altered mental status. He was started on empiric treatment for meningitis, but he continued to have progressive neurologic decline with the development of seizures, and died 9 days later. Autopsy of the brain showed liquefactive necrosis. Microscopy is as shown. What is the diagnosis?
What is the most likely diagnosis?
Acanthamoeba, Altered Mental Status, Granulomatous amebic encephalitis, Immunocompromised, Infectious Encephalitis