A Puzzling Case of Fever and a Pulsatile Hand

A 27-year-old presents with fever, weight loss, a heart murmur, and a rare ulnar artery aneurysm. Uncover the underlying systemic diagnosis.

Infective endocarditis


A 27-year-old man presented to the emergency department with abdominal pain in the left upper quadrant and a pulsatile, painful lesion on the right hand. He reported a 6-week history of fevers, decreased appetite, and night sweats and a weight loss of 12 kg. Physical examination was notable for a temperature of 38.5 degrees Celsius and a grade 3/6 diastolic murmur throughout the precordium. Laboratory studies revealed a white-cell count of 18,000 per cubic millimeter. CT angiography of the right arm revealed an aneurysm of the ulnar artery. What is the diagnosis?

What is the most likely diagnosis?

Systemic lupus erythematosus
Lyme disease
Infective endocarditis
Antiphospholipid syndrome
Kawasaki disease

Fever of unknown origin, Heart murmur, Infective endocarditis, Mycotic aneurysm, Septic embolism

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