A Sore Tongue and a Systemic Clue

A 50-year-old woman with Crohn’s disease presents with painful tongue and cheek lesions and Eosinophilia. Explore the diagnosis of this rare oral condition.

Pyostomatitis vegetans


A 50-year-old woman with a history of Crohn’s disease presented with 10 days of tongue and inner cheek pain. Laboratory studies showed an absolute eosinophil count of 870 per cubic millimeter (reference range, 50 to 500). What is the most likely diagnosis?

What is the most likely diagnosis?

Herpes simplex gingivostomatitis
Herpetic geometric glossitis
Lichen planus
Oral candidiasis
Pyostomatitis vegetans

Crohn’s disease, Eosinophilia, Inflammatory Bowel Disease, Oral Lesions, Pyostomatitis vegetans

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