A Transplant Patient’s Mysterious Rash

A 49-year-old transplant patient develops headache and diffuse, umbilicated papules. Explore the diagnosis of this life-threatening Opportunistic Infection.

Cryptococcus neoformans


A 49-year-old woman, who had undergone kidney transplantation 4 months earlier, presented to the emergency department with a 2-week history of headache, dizziness, and rash. On exam she had diffuse, umbilicated papules. What is the most likely pathogen?

What is the most likely diagnosis?

Blastomyces dermatitidis
Cryptococcus neoformans
Histoplasma capsulatum
Molluscum contagiosum
Mycobacterium tuberculosis

Cryptococcosis, Cryptococcus neoformans, Immunocompromised Host, Meningitis, Umbilicated Papules

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