A Window into Sickle Cell Disease

A 56-year-old man with sickle cell disease presents for a routine eye exam. Discover a significant anterior segment finding linked to proliferative Retinopathy.

Iris atrophy


A 56-year-old man with sickle hemoglobin C disease and proliferative sickle cell retinopathy presented for a routine eye examination. He was asymptomatic. What is seen on this examination of the anterior segment of the eye?

What is the most likely diagnosis?

Bilateral acute depigmentation of the iris (BADI)
Cornea verticillata
Iris atrophy
Mutton-fat keratic precipitates
Sunflower cataract

Iris atrophy, Ophthalmology, Retinopathy, Sickle Cell Disease, Vaso-occlusion

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