A Dark Sign in the Skin Folds

Insulin resistance
Discover the common endocrine condition linked to acanthosis nigricans, the velvety, dark skin patches in body folds. Learn its significance and management.
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Rapidly Enlarging Neck Swelling

Bleeding into a thyroid nodule
A 63-year-old man with a long-standing neck mass presents with a sudden, painful increase in its size. Explore the differential diagnosis and management.
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When Palms and Soles Turn Yellow

Diabetes mellitus
A patient presents with yellow discoloration of the palms and soles. Explore the differential diagnosis, including carotenemia, liver disease, and metabolic disorders.
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A Curious Case of Creamy Vessels

Hypertriglyceridemia
Explore a case where fundoscopy reveals milky, cream-colored retinal vessels. What systemic condition could cause such a dramatic ocular sign?
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The Case of the Enlarged Jaw

Bone scan
A patient presents with jaw pain and enlargement. Labs show high alkaline phosphatase and normal creatinine. What's the next step to confirm the diagnosis?
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A Tale of Two Brothers

Hypogonadism
An identical twin develops central adiposity, hair loss, and gynecomastia while his brother remains unaffected. Uncover the endocrine diagnosis in this case.
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When Skin Bumps Signal a Deeper Issue

Hypercholesterolemia
An 18-year-old presents with diffuse flat and tuberous xanthomas on the buttocks. Explore this case of skin findings pointing to a significant genetic disorder.
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When the Thyroid Goes South

Substernal goiter
A patient presents with tracheal deviation on chest X-ray. Neck ultrasound reveals a large goiter extending into the mediastinum. Explore the diagnosis.
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A Gassy Bladder Mystery

Diabetes mellitus
An abdominal X-ray reveals air in the urinary tract. What underlying condition predisposes patients to this rare and serious infection, emphysematous cystitis?
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A Case of a Swollen Neck & Staring Eyes

Graves' disease
Explore a medical case of a patient with a large nodular goiter, eyelid retraction, and diaphoresis. What is the underlying endocrine diagnosis?
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