Sweating, Weight Loss & a Neck Swelling

Graves' disease
A patient presents with diaphoresis, cachexia, and a diffusely enlarged thyroid. Explore the diagnostic process for this common endocrine disorder.
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A Puzzling Dermatological Finding

Graves' disease
A patient develops unusual skin lesions on their shins after thyroid surgery. Explore the underlying autoimmune condition linking the skin and the endocrine system.
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A Lump from a Lifetime of Insulin

Insulin lipohypertrophy
A patient with long-standing type 1 diabetes develops pendulous periumbilical masses. Explore a common complication of insulin therapy and its management.
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A Shocking Pelvic X-Ray Finding

Diabetes mellitus
Explore a case of bilateral vas deferens calcification on a pelvic radiograph. Learn about the differential diagnosis and the most common underlying condition.
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A Case of a Missing Thyroid

Ectopic thyroid
A patient presents with hypothyroidism and a solid midline neck mass. A thyroid scan reveals a surprising finding. Explore the diagnosis and management.
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When Urine Turns Dark in the Air

Ochronosis
A patient presents with urine that darkens on standing and unusual pigmentation of the sclera and ears. Explore this rare metabolic disorder.
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The Case of the Missing Knuckle

Albright's hereditary osteodystrophy
A patient presents with a missing fourth knuckle. Discover the rare genetic disorder behind this sign, its pathophysiology, and clinical implications.
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The Rugger-Jersey Spine

Fluorosis
Discover a rare cause of skeletal changes. A patient's spine shows a rugger-jersey appearance. What could be the surprising dietary source of this condition?
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Bilateral Fractures: A Deeper Look

Osteomalacia
Explore a case of bilateral femur fractures and osteopenia on a pelvic radiograph. Learn the key diagnostic features and differential diagnoses.
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A Curious Lesion on the Finger

Metastasis
A 50-year-old woman presents with a firm lesion on her finger. Radiography reveals a lytic bone lesion. What is the underlying diagnosis?
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