The Crystal Culprit of Joint Destruction

Gout
Challenge your diagnostic skills with this case of severe joint deformity. Learn about the pathophysiology and management of crystalline arthropathies.
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Beads on a String: A Vascular Mystery

Polyarteritis nodosa
Case study: A 19-year-old with fever, abdominal pain, and hypertension. See how renal artery microaneurysms on an angiogram led to a final diagnosis.
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A Painful Complication of Osteoporosis Therapy

Osteonecrosis
A patient on osteoporosis medication develops severe jaw pain. Explore the differential diagnosis and management of this serious drug-related complication.
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When Joints & Skin Stretch Too Far

Ehlers-Danlos syndrome
A patient presents with remarkable flexibility. What genetic condition affecting collagen could be the cause? Delve into the diagnosis and management.
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A Puzzling Case of Aching Joints

Sarcoidosis
A 43-year-old presents with bilateral hand and foot pain and an abnormal chest radiograph. Explore the differential diagnosis for this multisystem disorder.
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When Fingertips Disappear

Systemic sclerosis
A patient presents with Raynaud's phenomenon, skin tightening, and the unusual sign of missing fingertips. Explore the diagnosis behind acral osteolysis.
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A Closer Look at Hand Deformities

Osteoarthritis
Discover the common causes of hand joint deformities. Learn about Heberden's and Bouchard's nodes and what they signify for your joint health.
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When the Aorta Takes a Turn

Osteoporosis
A radiograph reveals a tortuous abdominal aorta. Explore an unusual underlying diagnosis related to vertebral compression fractures and subsequent height loss.
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Unraveling the Bamboo Spine

Ankylosing spondylitis
Explore a medical case featuring the classic 'bamboo spine' on an X-ray. What diagnosis is indicated by syndesmophytes and ligament calcification?
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Smoker’s Hand: When Fingers Turn White

Thromboangiitis obliterans
A smoker has a four-year history of blanching fingers in the cold. Learn about this vaso-occlusive disease of the extremities strongly linked to tobacco.
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