An X-ray of Hardened Skin

Scleroderma
A radiograph of the right arm reveals calcinosis cutis. Explore the differential diagnosis for this finding and discover the underlying systemic condition.
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Hardened Skin, A Deeper Cause

Systemic sclerosis
A case of calcinosis cutis. Explore the differential diagnosis for skin calcifications and discover the underlying systemic autoimmune condition.
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An Agonizing Elbow

Monosodium urate
A patient presents with acute elbow pain. Polarized microscopy of a joint aspirate reveals key diagnostic crystals. What is the underlying condition?
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A Painful Swelling with a Sharp Secret

Tophaceous gout
A patient presents with a mysterious swelling. Aspiration reveals a white fluid with distinct crystals. Can you determine the underlying diagnosis?
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Fever, Arthritis, & Abdominal Pain

Henoch-Schönlein purpura
A patient presents with a sudden onset of fever, painful joints, abdominal pain, and hematemesis. Explore the differential diagnosis for this vasculitis.
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A Young Woman’s Heart Attack

Polyarteritis nodosa
A 25-year-old woman on maintenance therapy presents with cardiac arrest. Explore the angiogram findings that reveal a rare underlying systemic cause.
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Fingers Changing Color in the Cold?

Raynaud's phenomenon
A patient presents with fingers that turn white and blue when exposed to cold. Explore the causes and management of this common vascular phenomenon.
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A Case of Extensive Calcification

Systemic sclerosis
A challenging case of calcinosis cutis with recurrent infections. Explore the differential diagnosis of this complex rheumatological condition.
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The Dry Eye & Facial Palsy Puzzle

Uveoparotid fever
Explore a complex case of a patient with dry eyes, dry mouth, parotid swelling, and facial palsy. Learn how hilar adenopathy points to a rare diagnosis.
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The Erlenmeyer Flask Deformity

Gaucher's disease
A 42-year-old man presents with chronic bone pain. Radiographs reveal an Erlenmeyer flask deformity of the femur. What is the underlying diagnosis?
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