Vision Loss and Headaches in SLE

Antiphospholipid syndrome
A 17-year-old with SLE presents with acute vision loss and chronic headaches. Explore the diagnostic process behind this complex ophthalmologic emergency.
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A Man with Mechanic’s Hands

Antisynthetase syndrome
A 37-year-old man presents with a chronic history of painful, cracked fingertips, muscle weakness, and fever. Explore the diagnostic journey.
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Salt-and-Pepper Skin & Shortness of Breath

Diffuse cutaneous systemic sclerosis
A 68-year-old man presents with interstitial lung disease and unique 'salt-and-pepper' skin changes. Explore this rheumatology case and its diagnosis.
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A Young Woman’s Rash & Aches

Systemic lupus erythematosus
Explore the case of a 34-year-old woman with a persistent cheek rash and joint pain. Learn about the key diagnostic markers and treatment approaches.
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Rash, Weakness & a Hidden Clue

Dermatomyositis
A 66-year-old woman presents with a pruritic rash and proximal muscle weakness. Discover the classic signs that point to a systemic autoimmune diagnosis.
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An Alarming Case of Headache & Vision Loss

Giant-cell arteritis
A 74-year-old woman presents with headaches, tongue swelling, and sudden blindness. Explore a rare complication of a common systemic vasculitis.
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A Decade of Digital Clubbing

Primary hypertrophic osteoarthropathy
A 31-year-old man presents with a 10-year history of digital clubbing and bone pain. Explore the diagnostic journey when common secondary causes are ruled out.
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A Puzzling Post-Infectious Rash

Keratoderma blenorrhagicum
A 40-year-old man develops a scaly foot rash, joint pain, and red eyes after an infection. Explore the diagnosis of this classic triad of symptoms.
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The Cold Truth About This Rash

Cryoglobulinemic vasculitis
A 67-year-old man with CLL presents with a painful, cold-induced rash. Explore the diagnosis of this purpuric vasculitis with low complement levels.
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Woody Skin & The ‘Groove Sign’

Eosinophilic fasciitis
A 66-year-old man presents with painful skin tightening and woody induration. Explore a case featuring the classic 'groove sign' and peripheral eosinophilia.
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